The 2025 Toyota Sequoia gets 20 to 22 miles per gallon combined, depending on the version. The best is the 2025 Sequoia 2WD at 22 mpg.
In the Standard Sport Utility Vehicle 2WD class for 2025, the Sequoia ranks 12th (tied with 2 others) of 21 for combined mileage (22 mpg), 6th (tied with 2 others) of 21 for yearly fuel cost ($2,850 for its cheapest version, cheapest first) and 10th of 21 for tailpipe CO2 (403 grams per mile for its lowest version, lowest first). The middle model of the class gets 23 mpg, costs $3,100 a year and puts out 407 grams per mile.
Across all 250 2025 models in the file that burn fuel, the middle best-version figure is 25 mpg and the highest is 57 mpg (Toyota Prius). Of the 249 other models, 168 get more miles per gallon than the 2025 Sequoia's best version, 19 other models get the same and 62 get less. The 2025 Sequoia's cheapest version costs $2,850 a year to fuel by the agency's figure; of the 241 other models with a cost figure, 110 cost less, 16 the same and 115 more.
Open the best-mileage list of this class for 2025. Cost and CO2 in the table are each model's lowest figure over its versions; plug-in hybrid and fuel-cell versions have no fuel cost and are left out of the cost column.
| Place | Model | Best version | mpg | Fuel a year, cheapest version | CO2 g/mi, lowest version |
|---|---|---|---|---|---|
| 6 | 2025 Lexus TX | 2025 TX 350 | 23 | $3,350 | 377 |
| 12 | 2025 Jeep Grand Cherokee | 2025 Grand Cherokee 2WD | 22 | $2,850 | 407 |
| 12 | 2025 Toyota 4Runner | 2025 4Runner 2WD #1 | 22 | $2,850 | 399 |
| 12 | 2025 Toyota SequoiaThis car | 2025 Sequoia 2WD | 22 | $2,850 | 403 |
| 15 | 2025 Lincoln Aviator | 2025 Aviator RWD | 21 | $2,950 | 425 |
| 16 | 2025 Dodge Durango | 2025 Durango RWD (6-cyl 3.6 L) | 20 | $3,100 | 439 |
| 16 | 2025 Jeep Wagoneer | 2025 Wagoneer 2WD | 20 | $3,100 | 453 |
Pick a 2025 version, then set your miles and fuel price. Fuel price as of 2026-11-14, U.S. Department of Energy / EPA. The price box starts at the dated price of the fuel the picked version burns (regular, midgrade or premium gasoline, diesel, E85 or electricity) and sets the price of that fuel. Miles are limited to 1,000 to 60,000 a year and the price to $0.01 to $20.00; a value outside that is worked out at the nearest limit.
2025 Sequoia 2WD, 6-cyl 3.4 L: 21 mpg city, 24 highway, 22 combined. The agency's own estimate for the 2025 Sequoia version is $2,850 a year (15,000 miles, the agency's fuel prices).
The 3 nearest rivals in the Standard Sport Utility Vehicle 2WD class for 2025, picked by closest combined mileage; only versions with a fuel-cost figure are listed. Same miles as on the left. The price box on the left is the price of the fuel of the version you picked: a rival that burns the same fuel uses that price, a rival that burns another fuel keeps the dated price of its own fuel. The 5-year line is 5 times the yearly gap.
Both cost the same to fuel.
Over 5 years both cost the same to fuel at these miles and these prices.
Dollar gaps use each car's best-mileage version.
| Rival in 2025 | Best version | Combined | Fuel a year, agency (15,000 miles) | Against the Sequoia (mileage) | Agency yearly fuel cost against the Sequoia | Side by side |
|---|---|---|---|---|---|---|
| 2025 Jeep Grand Cherokee | 2025 Grand Cherokee 2WD | 22 mpg | $2,850 | same figure | same | Compare |
| 2025 Toyota 4Runner | 2025 4Runner 2WD #1 | 22 mpg | $2,850 | same figure | same | Compare |
| 2025 Buick Enclave | 2025 Enclave FWD | 23 mpg | $2,700 | 1 higher | $150 less a year | - |
EPA test figures for 2025; the last column is the yearly fuel cost against the cheapest version.
| Version | Engine | Gearbox | Drive | City | Highway | Combined | Fuel a year | CO2 g/mi | Fuel vs cheapest |
|---|---|---|---|---|---|---|---|---|---|
| 2025 Sequoia 2WDHybrid | 6-cyl 3.4 L | Automatic (S10) | Rear-wheel | 21 | 24 | 22 | $2,850 | 403 | cheapest |
| 2025 Sequoia 4WDHybrid | 6-cyl 3.4 L | Automatic (S10) | Part-time 4-wheel | 19 | 22 | 20 | $3,100 | 439 | +$250 |
Enter the price difference you were quoted for the 2025 Sequoia; this page has no prices. Miles come from the calculator. The fuel price box there sets the price of the fuel of the version picked there; a version here that burns another fuel keeps the dated price of its own fuel. Versions with no fuel-cost figure are not listed.
Type the price difference you were quoted to see the payback.
Tailpipe CO2: the 2025 Sequoia 2WD puts out 403 grams per mile; across the 2 tested versions the figure runs from 403 to 439.
EPA scores (1 to 10, 10 best) for the 2025 Sequoia 2WD: fuel economy score 5 (4 to 5 across versions), greenhouse gas score 5 (4 to 5 across versions).
Best combined figure of the Sequoia gas version and hybrid each model year since 2016, set against the 2025 model.
| Model year | Best gas version | Best hybrid | Versions tested | Against 2025 | |
|---|---|---|---|---|---|
| 2016 | 15 mpg | none | 3 | 7 mpg lower than 2025 | |
| 2017 | 15 mpg | none | 3 | 7 mpg lower than 2025 | |
| 2018 | 15 mpg | none | 3 | 7 mpg lower than 2025 | |
| 2019 | 15 mpg | none | 2 | 7 mpg lower than 2025 | |
| 2020 | 15 mpg | none | 2 | 7 mpg lower than 2025 | |
| 2021 | 15 mpg | none | 2 | 7 mpg lower than 2025 | |
| 2022 | 15 mpg | none | 2 | 7 mpg lower than 2025 | |
| 2023 | none | 22 mpg | 2 | same as 2025 | |
| 2024 | none | 22 mpg | 2 | same as 2025 | |
| 2025This page | none | 22 mpg | 2 | this page | |
| 2026 | none | 22 mpg | 4 | same as 2025 |
Compared with the 2024 model: 2 versions were tested then and 2 now; the best figure went from 22 to 22 mpg (no change).
The 2026 model has 4 tested versions.
| Version in 2025 | 2025 | 2024 | Change |
|---|---|---|---|
| 2025 Sequoia 2WD, 6-cyl 3.4 L | 22 mpg | 22 mpg | no change |
| 2025 Sequoia 4WD, 6-cyl 3.4 L | 20 mpg | 20 mpg | no change |
The U.S. safety agency's model list has the 2025 Toyota Sequoia (as SEQUOIA HYBRID). The U.S. safety agency's ratings list returned no star ratings for the 2025 Toyota Sequoia on 2026-11-14. Not every model is crash tested, so this means "not rated by NHTSA", not a good or a bad result.
12 complaints for the 2025 Toyota Sequoia are on file (checked 2026-11-14). Complaints are reports that owners sent to the safety agency. They are not proven defects, and the counts are not adjusted for how many cars were sold.
| Part named in the reports | Reports | |
|---|---|---|
| Unknown Or Other | 5 | |
| Structure | 3 | |
| Air Bags | 1 | |
| Seat Belts | 1 | |
| Seats | 1 |
1 of the 12 reports say the car was in a crash, 0 mention a fire and 1 mentions an injury. One report can name more than one part.
2 recalls are on file for the 2025 Toyota Sequoia at the U.S. safety agency (checked 2026-11-14). A dealer does recall repairs free of charge.
Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2024-2025 Toyota Tundra, Tacoma Hybrid, Tacoma, RAV4 Hybrid, Land Cruiser Hybrid, Lexus GX550, 2024-2026 Tundra Hybrid, 2025 Sequoia Hybrid, Crown Signia, Grand Highlander, Lexus TX500 ...
Fix: Dealers will replace the load carrying capacity modification label, free of charge. Owner letters were mailed May 26, 2026. Owners may contact Toyota's customer service at 1-800-331-4331.
Toyota Motor Engineering & Manufacturing (Toyota) is recalling certain 2022-2025 Tundra, Tundra Hybrid, and 2023-2025 Sequoia Hybrid vehicles. A software error may cause the rearview image not to display when the vehicle is placed in reverse.
Fix: Dealers will update the multimedia display software, free of charge. Owner notification letters were mailed November 19, 2025. Owners may contact Toyota's customer service at 1-800-331-4331.
Other 2025 models of the same agency class, each with its best combined figure. The Sequoia itself is at 22 mpg.
More Toyota models that have a 2025 page here, with the class of each and its best combined figure.
The 2025 Sequoia 2WD with 22 mpg combined (21 city, 24 highway).
The 2025 Toyota Sequoia costs between $2,850 and $3,100 to fuel by the agency's estimate, which assumes 15,000 miles a year. The cheapest is the 2025 Sequoia 2WD at $2,850; the dearest is the 2025 Sequoia 4WD at $3,100. Use the calculator above for your own miles and fuel price.
2025 Sequoia 4WD: 20 mpg combined (19 city, 22 highway).
The 2025 Toyota Sequoia is 12th of 21 for combined mileage. The top of the class is the 2025 Toyota Grand Highlander at 36 mpg, and the middle figure for the class is 23 mpg. In the list, the next one ahead is the 2025 Toyota 4Runner at 22 mpg and the next one behind is the 2025 Lincoln Aviator at 21 mpg.
The 2024 model had 2 tested versions and the 2025 model has 2. The best figure went from 22 to 22 mpg (no change).
No star ratings were returned for the 2025 Toyota Sequoia on 2026-11-14. Not every model is crash tested.
12 complaints for the 2025 Toyota Sequoia are on file at the safety agency (checked 2026-11-14); the part named most often is Unknown Or Other (5 reports). Complaints are reports owners sent in, not proven defects.
The agency's database lists 2 recalls for the 2025 Toyota Sequoia (checked 2026-11-14). They are listed above with the repair the maker offers.
For the 2025 Toyota Sequoia: EPA file 2026-11-04; fuel price 2026-11-14; crash tests 2026-11-14 (no stars returned); complaints 2026-11-14; recalls 2026-11-14. Not covered: purchase price, towing, reliability, repair and insurance costs.
Mileage and fuel cost for the 2025 Toyota Sequoia: U.S. Environmental Protection Agency, fueleconomy.gov vehicle file (file dated 2026-11-04). Recalls for the 2025 Toyota Sequoia: U.S. National Highway Traffic Safety Administration (checked 2026-11-14). Crash-test ratings for the 2025 Toyota Sequoia: NHTSA 5-Star Safety Ratings (checked 2026-11-14). Complaints for the 2025 Toyota Sequoia: NHTSA (checked 2026-11-14). Fuel prices: U.S. Department of Energy / EPA (2026-11-14). Your own mileage depends on how and where you drive. Where our numbers come from.